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Comparing Retinoids used in Private Label Skin Care

Retinoids, derivatives of vitamin A, are powerhouse ingredients used in cosmetics hence an important ingredient to consider in Private Label Skincare. They are celebrated for their ability to promote cell turnover, boost collagen production, and address concerns like acne, hyperpigmentation, and aging. The most common retinoids in skincare are retinol, retinaldehyde, and retinyl palmitate, with new generation retinoids such as Hydroxypinacolone Retinoate (HPR) making an appearance. Each varies in potency, stability, and skin compatibility, so choosing the right one to use is very important. This article compares the differences of these retinoids based on their efficacy, irritation potential, and application in cosmetics.


Retinyl Palmitate: Retinyl palmitate is an ester of retinoic acid, the least potent retinoid. It requires a three step enzymatic conversion (retinyl palmitate converts to retinol, then to retinaldehyde, and finally to retinoic acid) in the skin to become active retinoic acid, which limits its efficacy. Found in many over-the-counter products, it’s gentle and well-tolerated, making it ideal for beginners or sensitive skin. Retinyl palmitate offers only mild benefits, such as improved skin texture and hydration, but its effects on wrinkles or acne are slower and less pronounced. Its stability in formulations makes it a popular choice for cheaper moisturizers, but results are very subtle compared to stronger retinoids. For this reason we do not use recommend nor use this form of Vitamin A in our Private Label Skin care range.



Private Label skin care retinoid use

Retinol: Retinol, a step closer to retinoic acid, is more potent than retinyl palmitate but still requires a two step conversion to retinaldehyde and then another into retinoic acid. Widely used in anti-aging and acne treatments, retinol is effective at reducing fine lines, unclogging pores, and evening skin tone. Concentrations typically range from 0.1% to 1%, with higher strengths delivering faster results but increasing irritation risk. Retinol’s chemical instability and potential for causing skin irritation are the main downsides of its use thus why gradual introduction is advised to minimize redness or peeling.


Retinaldehyde: Retinaldehyde (or retinal) is one step away from retinoic acid, making it more potent than retinol. Its direct conversion to retinoic acid enhances its bioactivity, making it a favorite in high-performance serums. It delivers faster results in reducing hyperpigmentation, smoothing wrinkles, and treating acne. Found in concentrations typically of 0.05% to 0.1%, retinaldehyde, like retinol, also has the potential for causing skin irritation and thus usually requires a slow integration into skin care routines to avoid such reactions. Another disadvantage of retinaldehyde is that it is even less chemically stable than retinol.


Hydroxypinacolone Retinoate (HPR): HPR, a newer retinoid ester, is often marketed as “granactive retinoid” for its direct binding to retinoid receptors without any conversion. This unique mechanism offers retinoic acid-like benefits with significantly less irritation, making HPR a game-changer for sensitive skin. Typically available in concentrations of 0.05% to 0.2%, HPR improves skin texture, reduces fine lines, and addresses acne with minimal side effects. Its stability and compatibility with other actives, like vitamin C, enhance its versatility in formulations. HPR’s gentle yet effective profile positions it as a modern superior alternative to traditional retinoids.


Considerations: Retinyl palmitate is the gentlest but least effective so not recommended if your after visible results unless your a beginner. Retinol offers a balance of efficacy and accessibility but may irritate sensitive skin and is unstable. Retinaldehyde provides faster, stronger results with moderate irritation but is more unstable than retinol, while HPR delivers high efficacy with minimal discomfort and is highly stable. It is for this reason we chose to use the HPR form of Vitamin A in our Private Label Skin Care range as it is currently the best option.

 
 
 
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